Latest imported 13F data

TANG CAPITAL MANAGEMENT LLC

โ€ขCIK: 1232621โ€ขFiling: Q4 2025

**TANG CAPITAL MANAGEMENT LLC** manages $2.0B across a diversified portfolio of 75 positions. The firm maintains significant exposure to key names, notably anchoring its top holdings with AUPH at $180.7M and GLPG at $128.2M. Further concentration is evident in PTCT ($113.9M) and CELC ($104.7M), suggesting a conviction-driven approach within its investment mandate. This structure highlights tactical allocation across several high-conviction names.

Total AUM
$2.0B
QoQ Performance
-22.1%
Positions
75
Top 10 Concentration
52.9%
Latest Filing
Q4 2025

Top Holdings Allocation

AUPH
GLPG
PTCT
CELC
AUPH8.9%
GLPG6.3%
PTCT5.6%
CELC5.2%
MIRM4.8%
TARS4.8%
KINIKSA4.6%
IMCR4.5%

๐Ÿ“ˆ Biggest Buys

RNA
AVIDITY BIOSCIENCES INC
NEW
3.2% of portfolio
CAPR
CAPRICOR THERAPEUTICS INC
NEW
2.4% of portfolio
SPY
SPDR S&P 500 ETF TR
NEW
1.0% of portfolio
BNTX
BIONTECH SE
+74.1%
2.2% of portfolio
BSFA
ANI PHARMACEUTICALS INC
+51.6%
1.9% of portfolio

๐Ÿ“‰ Biggest Sells

TARS
TARSUS PHARMACEUTICALS INC
-51.6%
4.8% of portfolio
SYRE
SPYRE THERAPEUTICS INC
-40.9%
3.1% of portfolio
VRDN
VIRIDIAN THERAPEUTICS INC
-36.9%
2.8% of portfolio
ACAD
ACADIA PHARMACEUTICALS INC
-80.0%
0.4% of portfolio
PGEN
PRECIGEN INC
-54.7%
1.2% of portfolio

Sector Breakdown

Other96.5%
Technology1.9%
ETF1.0%
Healthcare0.5%

๐Ÿšช Exited Positionssold since Q3 2025

2GH
MERUS N V
SOLD
$56.5M
RLAY
RELAY THERAPEUTICS INC
SOLD
$42.1M
VERA
VERA THERAPEUTICS INC CL A
SOLD
$39.2M
NKE
NIKE INC
SOLD
$36.2M
IONS
IONIS PHARMACEUTICALS INC
SOLD
$36.0M
+123 more exited positions

Changes from Q3 2025

NEW9 new positions
โ†‘12 increased
โ†“38 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022