Latest imported 13F data
SYRE

SPYRE THERAPEUTICS INC

Institutional Ownership · Q4 2025

Filing: Q4 2025

SPYRE THERAPEUTICS INC (SYRE) is held by 147 institutional investors with combined holdings of $2.7B. Major holders include FMR LLC, BlackRock, Inc., RTW INVESTMENTS, LP.

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Institutional Holders
147
Total Value
$2.7B
Ownership %
93.2%

🏦 Top Institutional Holders

FMR LLC
11.6M shares
$381.3M
13.40% ownership
BlackRock, Inc.
5.5M shares
$180.9M
6.36% ownership
RTW INVESTMENTS, LP
4.2M shares
$136.7M
4.80% ownership
VANGUARD GROUP INC
4.0M shares
$132.2M
4.65% ownership
Fairmount Funds Management LLC
4.0M shares
$131.6M
4.63% ownership

📊 Financials

Income statement, balance sheet, and cash flow from SEC filings.

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