Data as of Q4 2025 (Dec 31, 2025)
UPB

UPSTREAM BIO INC

Institutional Ownership · Q4 2025

Filing: Q4 2025

UPSTREAM BIO INC (UPB) is held by 128 institutional investors with combined holdings of $1.4B. Major holders include FMR LLC, ORBIMED ADVISORS LLC, BlackRock, Inc. (BLK).

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Institutional Holders
128
Total Value
$1.4B
Ownership %
93.9%

🏦 Top Institutional Holders

FMR LLC
7.5M shares
$204.1M
13.82% ownership
ORBIMED ADVISORS LLC
5.7M shares
$154.6M
10.46% ownership
BlackRock, Inc. (BLK)
3.3M shares
$90.8M
6.15% ownership
Decheng Capital LLC
3.1M shares
$85.3M
5.78% ownership
NORGES BANK
2.9M shares
$78.3M
5.30% ownership

📊 Financials

Income statement, balance sheet, and cash flow from SEC filings.

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