Data as of Q4 2025 (Dec 31, 2025)
SPRO

SPERO THERAPEUTICS INC

Institutional Ownership · Q4 2025

Filing: Q4 2025

SPERO THERAPEUTICS INC (SPRO) is held by 55 institutional investors with combined holdings of $49M. Major holders include GSK plc (GSK, GLAXF), PFIZER INC (PFE), VANGUARD GROUP INC.

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Institutional Holders
55
Total Value
$48.6M
Ownership %
36.0%

🏦 Top Institutional Holders

GSK plc (GSK, GLAXF)
9.2M shares
$21.4M
15.87% ownership
PFIZER INC (PFE)
2.4M shares
$5.5M
4.08% ownership
VANGUARD GROUP INC
2.1M shares
$4.9M
3.60% ownership
RENAISSANCE TECHNOLOGIES LLC
1.3M shares
$3.0M
2.21% ownership
Alphabet Inc. (GOOG, GOOGL)
890.0K shares
$2.1M
1.54% ownership

📊 Financials

Income statement, balance sheet, and cash flow from SEC filings.

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