Sio Capital Management, LLC
•CIK: 1482416•Filing: Q4 2025
**Sio Capital Management, LLC** manages $636M across a diversified portfolio of 68 positions. The firm maintains significant concentration in technology and growth sectors, highlighted by top holdings including CELC ($47.6M), CI ($47.4M), and SNY ($47.1M). These top three positions alone represent over $142M of the fund's current assets. Sio's active management approach is evident through its substantial allocations across multiple high-conviction names.
Total AUM
$603.2M
+ $32.6M in options
QoQ Performance
+52.6%
Positions
65
+ 3 options
Top 10 Concentration
53.7%
Latest Filing
Q4 2025
Top Holdings Allocation
CELC
CI
SNY
MMS
ZBH
CELC7.5%
CI7.5%
SNY7.4%
MMS6.8%
ZBH5.5%
RYTM4.5%
KVUE4.0%
OGN3.9%
📈 Biggest Buys
📉 Biggest Sells
Sector Breakdown
Other92.5%
Healthcare7.5%
🚪 Exited Positionssold since Q3 2025
+5 more exited positions
Changes from Q3 2025
NEW27 new positions
↑8 increased
↓16 decreased
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023