Data as of Q4 2025 (Dec 31, 2025)

SILVERARC CAPITAL MANAGEMENT, LLC

โ€ขCIK: 1816307โ€ขFiling: Q4 2025

**SILVERARC CAPITAL MANAGEMENT, LLC** manages $720M across a diversified portfolio of 68 positions. The fund exhibits significant conviction in select names, with top holdings including ABVX at $56.9M and COGT at $44.2M. Further concentration is evident in BCLYF ($40.7M) and KALV ($39.2M), suggesting a focused, high-conviction investment mandate. This structure indicates active capital deployment into specific market segments.

Total AUM
$691.1M
+ $28.9M in options
QoQ Performance
+0.1%
Positions
64
+ 4 options
Top 10 Concentration
49.7%
Latest Filing
Q4 2025

Top Holdings Allocation

ABVX
COGT
UROG
KALV
CELC
ABVX7.9%
COGT6.1%
UROGEN5.7%
KALV5.4%
CELC5.2%
NUVL4.4%
DNTH4.3%
KOD4.0%

๐Ÿ“ˆ Biggest Buys

CELC
CELCUITY INC
+323.0%
5.2% of portfolio
IMNM
IMMUNOME INC
NEW
3.4% of portfolio
โ€”CALL
UNIQURE NV
NEW
2.4% of portfolio
KALV
KALVISTA PHARMACEUTICALS INC
+78.0%
5.4% of portfolio
COGT
COGENT BIOSCIENCES INC
+52.8%
6.1% of portfolio

๐Ÿ“‰ Biggest Sells

RYTM
RHYTHM PHARMACEUTICALS INC
-63.3%
2.0% of portfolio
IM8N
INSMED INC
-65.5%
1.7% of portfolio
OLMA
OLEMA PHARMACEUTICALS INC
-77.9%
0.7% of portfolio
ABVX
ABIVAX SA
-21.8%
7.9% of portfolio
CGON
CG ONCOLOGY INC
-43.4%
2.1% of portfolio

Sector Breakdown

Other98.6%
Healthcare1.4%

๐Ÿšช Exited Positionssold since Q3 2025

RNAGBP
AVIDITY BIOSCIENCES INC
SOLD
$36.8M
AKRO
AKERO THERAPEUTICS INC
SOLD
$30.6M
โ€”
UNITED THERAPEUTICS CORP DEL
SOLD
$25.1M
CDTX
CIDARA THERAPEUTICS INC
SOLD
$21.2M
CYTK
CYTOKINETICS INC
SOLD
$11.6M
+30 more exited positions

Changes from Q3 2025

NEW21 new positions
โ†‘18 increased
โ†“27 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023