Data as of Q4 2025 (Dec 31, 2025)

Mass General Brigham, Inc

•CIK: 1678378•Filing: Q4 2025

**Mass General Brigham, Inc.** manages $810M across a concentrated portfolio of 7 holdings. The fund exhibits a significant overweighting in ACWI, representing $652.8M of its total assets. Notable allocations include substantial positions in KRMN ($114.3M) and RVMD ($27.4M). This structure suggests a targeted, multi-sector approach anchored by its largest single holding.

Total AUM
$809.8M
QoQ Performance
N/A
Positions
7
Top 10 Concentration
100.0%
Latest Filing
Q4 2025

Top Holdings Allocation

ACWI
KRMN
ACWI80.6%
KRMN14.1%
RVMD3.4%
MAZE1.2%
TNGX0.4%
MDLN0.1%
RBRK0.1%

📈 Biggest Buys

ACWI
ISHARES TR
NEW
80.6% of portfolio
KRMN
KARMAN HLDGS INC
NEW
14.1% of portfolio
MAZE
MAZE THERAPEUTICS INC
NEW
1.2% of portfolio
MDLN
MEDLINE INC
NEW
0.1% of portfolio
RBRK
RUBRIK INC
NEW
0.1% of portfolio

📉 Biggest Sells

No reductions this quarter

Sector Breakdown

Other100.0%

🚪 Exited Positionssold since Q3 2024

IOT
SAMSARA INC
SOLD
$21.6M
PLRX
PLIANT THERAPEUTICS INC
SOLD
$3.2M
FULC
FULCRUM THERAPEUTICS INC
SOLD
$733.1K

Changes from Q3 2024

NEW5 new positions
↑1 increased

Historical Filings

Q4 2025Q3 2024Q2 2024Q1 2024Q4 2023

📌 Top Holdings

ACWI80.6%
ISHARES TR
$652.8M
KRMN14.1%
KARMAN HLDGS INC
$114.3M
RVMD3.4%
REVOLUTION MEDICINES INC
$27.4M
MAZE1.2%
MAZE THERAPEUTICS INC
$9.9M
TNGX0.4%
TANGO THERAPEUTICS INC
$3.1M

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