Data as of Q4 2025 (Dec 31, 2025)

Ishara Investments LP

โ€ขCIK: 2111609โ€ขFiling: Q4 2025

**Ishara Investments LP** manages $87M across a concentrated portfolio of 38 positions. The fund exhibits significant conviction in select names, with PRAX representing the largest allocation at $11.8M. Key holdings also include XERS ($6.3M), BMRN ($5.9M), and AM6 ($5.1M), indicating a focused, high-conviction approach. This structure suggests active, thematic capital deployment across specialized sectors.

Total AUM
$85.9M
+ $1.5M in options
QoQ Performance
N/A
Positions
37
+ 1 option
Top 10 Concentration
55.9%
Latest Filing
Q4 2025

Top Holdings Allocation

PRAX
XERS
BMRN
AM6
PRAX13.5%
XERS7.2%
BMRN6.8%
AM65.9%
ACAD4.9%
ANNX4.3%
NUVB4.1%
BBIO3.1%

๐Ÿ“ˆ Biggest Buys

PRAX
PRAXIS PRECISION MEDICINES I
NEW
13.5% of portfolio
XERS
XERIS BIOPHARMA HOLDINGS INC
NEW
7.2% of portfolio
BMRN
BIOMARIN PHARMACEUTICAL INC
NEW
6.8% of portfolio
AM6
AMICUS THERAPEUTICS INC
NEW
5.9% of portfolio
ACAD
ACADIA PHARMACEUTICALS INC
NEW
4.9% of portfolio

๐Ÿ“‰ Biggest Sells

No reductions this quarter

Sector Breakdown

Other100.0%