HighVista Strategies LLC
•CIK: 1335325•Filing: Q4 2025
**HighVista Strategies LLC** manages $388M across a diversified portfolio of 145 positions. The fund exhibits concentrated exposure, with top holdings including DBC at $23.6M and GPCR at $13.4M. Further significant allocations are directed toward COGT ($12.0M), VRDN ($11.6M), and ABVX ($9.7M). This structure suggests a tactical, high-conviction approach across multiple sectors.
Total AUM
$388.3M
QoQ Performance
-4.8%
Positions
145
Top 10 Concentration
28.1%
Latest Filing
Q4 2025
Top Holdings Allocation
DBC
DBC6.1%
GPCR3.5%
COGT3.1%
VRDN3.0%
ABVX2.5%
RVMD2.5%
PRAX2.0%
NUVL1.9%
📈 Biggest Buys
📉 Biggest Sells
Sector Breakdown
Other92.2%
Technology3.8%
Consumer1.4%
Financial1.3%
Industrial0.6%
Utilities0.4%
Healthcare0.3%
🚪 Exited Positionssold since Q3 2025
+31 more exited positions
Changes from Q3 2025
NEW33 new positions
↑26 increased
↓86 decreased
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023