Data as of Q4 2025 (Dec 31, 2025)

Foresite Capital Management VI LLC

•CIK: 2013341•Filing: Q4 2025

**Foresite Capital Management VI LLC** manages $331M across a concentrated portfolio of 12 positions. The fund exhibits significant conviction in select names, with its largest holding in CGON accounting for $92.2M. Further notable allocations include RAPT at $52.9M and ALMS at $41.5M, indicating a focused, high-conviction investment mandate. This structure suggests a tactical approach targeting outsized returns within specific market segments.

Total AUM
$330.8M
QoQ Performance
+27.8%
Positions
12
Top 10 Concentration
94.9%
Latest Filing
Q4 2025

Top Holdings Allocation

CGON
RAPT
ALMS
CNTA
VSTM
CGON27.9%
RAPT16.0%
ALMS12.5%
CNTA10.3%
VSTM7.3%
DNLI5.0%
NTRA4.7%
AGIO4.4%

📈 Biggest Buys

NTRA
Natera, Inc.
NEW
4.7% of portfolio
AGIO
AGIOS PHARMACEUTICALS, INC.
NEW
4.4% of portfolio
—
Atai Beckley N.V.
NEW
3.4% of portfolio
VSTM
Verastem, Inc.
+19.9%
7.3% of portfolio
CNTA
Centessa Pharmaceuticals plc
+3.8%
10.3% of portfolio

📉 Biggest Sells

CRVS
Corvus Pharmaceuticals, Inc.
-20.2%
3.2% of portfolio

Sector Breakdown

Other100.0%

🚪 Exited Positionssold since Q3 2025

AKRO
Akero Therapeutics, Inc.
SOLD
$11.6M
RNAGBP
Avidity Biosciences, Inc.
SOLD
$1.7M
—
CASI Pharmaceuticals, Inc.
SOLD
$1.6M

Changes from Q3 2025

NEW3 new positions
↑2 increased
↓1 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024

📌 Top Holdings

CGON27.9%
CG Oncology, Inc.
$92.2M
RAPT16.0%
RAPT Therapeutics, Inc.
$52.9M
ALMS12.5%
ALUMIS INC.
$41.5M
CNTA10.3%
Centessa Pharmaceuticals plc
$34.1M
VSTM7.3%
Verastem, Inc.
$24.2M

⚖️ Compare Fund

Compare this fund's holdings with other hedge funds.

🎯 Fund Movement Signals

See AI-analyzed fund movement signals and accumulation patterns.

👤 Insider Trading

See what corporate insiders are buying and selling.