Data as of Q4 2025 (Dec 31, 2025)

Flagship Pioneering, LLC

โ€ขCIK: 1400240โ€ขFiling: Q4 2025

**Flagship Pioneering Inc.** manages $324M across a concentrated portfolio of four holdings. The fund exhibits a significant overweight to biotechnology, anchored by a substantial $136.6M position in MRNA. Further allocations include $101.8M in SANA and $68.4M in FHTX, indicating a deep conviction in transformative life science platforms. This structure suggests a high-conviction, venture-style approach targeting breakthrough innovation.

Total AUM
$324.0M
QoQ Performance
+10.7%
Positions
4
Top 10 Concentration
100.0%
Latest Filing
Q4 2025

Top Holdings Allocation

MRNA
SANA
FHTX
MCRB
MRNA42.2%
SANA31.4%
FHTX21.1%
MCRB5.3%

๐Ÿ“ˆ Biggest Buys

No new positions or increases this quarter

๐Ÿ“‰ Biggest Sells

No reductions this quarter

Sector Breakdown

Other100.0%

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023