Data as of Q4 2025 (Dec 31, 2025)

Checkpoint Capital L.P.

โ€ขCIK: 1977548โ€ขFiling: Q4 2025

**Checkpoint Capital L.P.** manages $316M across a concentrated portfolio of six positions. The fund exhibits significant conviction in its top holdings, led by ARGX, representing $119.4M, and RYTM, at $106.2M. These two names alone account for over 70% of the reported assets. The remaining allocation includes strategic bets on IRON ($36.0M), RVMD ($29.5M), HTD ($14.0M), and CYTK ($10.6M).

Total AUM
$315.6M
QoQ Performance
+5.8%
Positions
6
Top 10 Concentration
100.0%
Latest Filing
Q4 2025

Top Holdings Allocation

ARGX
RYTM
IRON
RVMD
ARGX37.8%
RYTM33.6%
IRON11.4%
RVMD9.3%
HTD4.4%
CYTK3.4%

๐Ÿ“ˆ Biggest Buys

RYTM
RHYTHM PHARMACEUTICALS INC
+29.9%
33.6% of portfolio
CYTK
CYTOKINETICS INC
+343.8%
3.4% of portfolio
IRON
DISC MEDICINE INC
+5.3%
11.4% of portfolio
HTD
CORCEPT THERAPEUTICS INC
+2.3%
4.4% of portfolio

๐Ÿ“‰ Biggest Sells

RVMD
REVOLUTION MEDICINES INC
-24.8%
9.3% of portfolio
ARGX
ARGENX SE
-5.3%
37.8% of portfolio

Sector Breakdown

Other100.0%

๐Ÿšช Exited Positionssold since Q3 2025

CRNX
CRINETICS PHARMACEUTICALS IN
SOLD
$10.8M
SEPN
SEPTERNA INC
SOLD
$5.3M
STOK
STOKE THERAPEUTICS INC
SOLD
$5.0M
KYMR
KYMERA THERAPEUTICS INC
SOLD
$3.5M

Changes from Q3 2025

โ†‘4 increased
โ†“2 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023