Data as of Q4 2025 (Dec 31, 2025)

Catalio Capital Management, LP

โ€ขCIK: 1958125โ€ขFiling: Q4 2025

**Catalio Capital Management, LP** manages $566M across a portfolio of 45 positions, exhibiting a concentrated focus on the healthcare sector. Top holdings include GILD at $35.5M and BMY at $34.9M, anchoring significant exposure to pharmaceutical and biotech names. The fund maintains substantial allocations to industry leaders such as BSX ($34.4M), BBOT ($31.4M), and LLY ($27.9M). This positioning suggests a deep, conviction-driven approach within the life sciences value chain.

Total AUM
$565.8M
QoQ Performance
+4.6%
Positions
45
Top 10 Concentration
51.2%
Latest Filing
Q4 2025

Top Holdings Allocation

GILD
BMY
BSX
BBOT
GILD6.3%
BMY6.2%
BSX6.1%
BBOT5.6%
LLY4.9%
DNTH4.8%
ASND4.5%
SNDX4.4%

๐Ÿ“ˆ Biggest Buys

GILD
GILEAD SCIENCES INC
NEW
6.3% of portfolio
BMY
BRISTOL-MYERS SQUIBB CO
NEW
6.2% of portfolio
BBOT
BRIDGEBIO ONCOLOGY THERAPEUT
NEW
5.6% of portfolio
JNJ
JOHNSON & JOHNSON
NEW
4.4% of portfolio
EW
EDWARDS LIFESCIENCES CORP
NEW
2.8% of portfolio

๐Ÿ“‰ Biggest Sells

LLY
ELI LILLY & CO
-54.8%
4.9% of portfolio
GPCR
STRUCTURE THERAPEUTICS INC
-61.2%
3.1% of portfolio
ISRG
INTUITIVE SURGICAL INC
-61.9%
2.7% of portfolio
NTRA
NATERA INC
-58.0%
2.5% of portfolio
CYTK
CYTOKINETICS INC
-42.8%
2.9% of portfolio

Sector Breakdown

Other78.2%
Healthcare21.8%

๐Ÿšช Exited Positionssold since Q3 2025

ABBV
ABBVIE INC
SOLD
$35.9M
BBIO
BRIDGEBIO PHARMA INC
SOLD
$32.3M
EXK
EXACT SCIENCES CORP
SOLD
$13.6M
RNAGBP
AVIDITY BIOSCIENCES INC
SOLD
$11.5M
CDTX
CIDARA THERAPEUTICS INC
SOLD
$5.1M
+2 more exited positions

Changes from Q3 2025

NEW14 new positions
โ†‘5 increased
โ†“20 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024