Data as of Q4 2025 (Dec 31, 2025)·Next filing deadline: May 15, 2026

BRAIDWELL LP

•CIK: 1920938•Filing: Q4 2025

BRAIDWELL LP, managed by the seasoned duo of John Braidwell and his team, is known for its concentrated, high-conviction bets, currently holding 73 positions with a focus on healthcare and technology sectors. Recently, the fund has made notable moves by adding FULCRUM THERAPEUTICS and SERENITY BIOPHARMA, up 161.5% and 489% respectively, while exiting positions in STT-PG and KPTI.

Total AUM

$2.6B

QoQ Performance

+5.6%

Positions

68

Top 10 Concentration

37.2%

Latest Filing

Q4 2025

Top Holdings Allocation

CAI

CAI8.1%

EWTX5.0%

NBIX4.1%

GKOS4.0%

NUVL3.2%

XENE3.1%

CGON3.0%

HNGE2.3%

📈 Biggest Buys

KODIAK SCIENCES INC

NEW

2.2% of portfolio

CENTESSA PHARMACEUTICALS PLC

NEW

2.1% of portfolio

BRIGHTSPRING HEALTH SVCS INC

NEW

1.7% of portfolio

NURIX THERAPEUTICS INC

NEW

1.6% of portfolio

ILLUMINA INC

NEW

1.4% of portfolio

📉 Biggest Sells

XENON PHARMACEUTICALS INC

-49.4%

3.1% of portfolio

KRYSTAL BIOTECH INC

-61.2%

1.9% of portfolio

APOGEE THERAPEUTICS INC

-60.0%

1.7% of portfolio

CG ONCOLOGY INC

-43.0%

3.0% of portfolio

DANAHER CORPORATION

-61.8%

1.0% of portfolio

Sector Breakdown

Other95.5%

Healthcare4.5%

🚪 Exited Positionssold since Q3 2025

GLOBUS MED INC

SOLD

$28.5M

TENET HEALTHCARE CORP

SOLD

$24.7M

EXACT SCIENCES CORP

SOLD

$22.7M

AKERO THERAPEUTICS INC

SOLD

$22.6M

ALPHATEC HLDGS INC

SOLD

$22.0M

+11 more exited positions

Changes from Q3 2025

NEW20 new positions

↑16 increased

↓29 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023

📌 Top Holdings

CARIS LIFE SCIENCES INC

EDGEWISE THERAPEUTICS INC

NEUROCRINE BIOSCIENCES INC

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