Data as of Q4 2025 (Dec 31, 2025)

Atlas Venture Life Science Advisors, LLC

โ€ขCIK: 1917529โ€ขFiling: Q4 2025

**Atlas Venture Life Science Advisors, LLC** manages $865M across a concentrated portfolio of 8 positions. The fund exhibits a significant conviction in key life science names, with KYMR representing the largest holding at $362.6M. Further substantial allocations include DYN at $178.6M and SION at $123.2M, indicating a deep focus on high-growth, specialized biopharma opportunities. This concentrated structure suggests a highly selective, deep-dive approach within the life sciences sector.

Total AUM
$865.2M
QoQ Performance
+14.9%
Positions
8
Top 10 Concentration
100.0%
Latest Filing
Q4 2025

Top Holdings Allocation

KYMR
DYN
SION
IRON
DAWN
KYMR41.9%
DYN20.6%
SION14.2%
IRON13.9%
DAWN6.9%
KRRO1.1%
QTTB0.8%
Generation0.5%

๐Ÿ“ˆ Biggest Buys

โ€”
Generation Bio, Co.
NEW
0.5% of portfolio

๐Ÿ“‰ Biggest Sells

IRON
Disc Medicine, Inc.
-29.3%
13.9% of portfolio
SION
Sionna Therapeutics, Inc.
-17.1%
14.2% of portfolio
KYMR
Kymera Therapeutics, Inc.
-4.8%
41.9% of portfolio
DAWN
Day One Biopharmaceuticals, Inc.
-0.3%
6.9% of portfolio

Sector Breakdown

Other100.0%

๐Ÿšช Exited Positionssold since Q3 2025

GBIOGBX
Generation Bio, Co.
SOLD
$5.1M
IMA
ImageneBio, Inc.
SOLD
$3.1M

Changes from Q3 2025

NEW1 new position
โ†“4 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023