Data as of Q4 2025 (Dec 31, 2025)
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Showing Q1 2025 data
Aquilo Capital Management, LLC's Q4 2025 filing not yet available. Expected by Feb 14, 2026.

Aquilo Capital Management, LLC

โ€ขCIK: 1591986โ€ขFiling: Q1 2025

**Aquilo Capital Management, LLC** is a focused investment manager overseeing $56M in assets. The fund maintains a concentrated portfolio of 13 positions, with significant allocations to biotechnology and healthcare names. Top holdings include AMGN at $18.7M, followed by 2L9 ($7.4M) and ARWR ($7.0M). This structure suggests a deep-value, sector-specific approach within the life sciences space.

Total AUM
$37.1M
+ $18.7M in options
QoQ Performance
-36.5%
Positions
12
+ 1 option
Top 10 Concentration
93.4%
Latest Filing
Q1 2025

Top Holdings Allocation

AMGN
2L9
ARWR
PTGX
KYMR
DTIL
AMGN33.5%
2L913.3%
ARWR12.6%
PTGX7.1%
KYMR6.8%
DTIL6.2%
ARVN4.5%
RGNX3.5%

๐Ÿ“ˆ Biggest Buys

AMGNCALL
AMGEN INC
+140.0%
33.5% of portfolio
ZYME
ZYMEWORKS INC
NEW
1.8% of portfolio
DTIL
PRECISION BIOSCIENCES INC
+35.4%
6.2% of portfolio
PTGX
PROTAGONIST THERAPEUTICS INC
+6.7%
7.1% of portfolio
ARVN
ARVINAS INC
+9.7%
4.5% of portfolio

๐Ÿ“‰ Biggest Sells

2L9
BLUEPRINT MEDICINES CORP
-35.2%
13.3% of portfolio
ARWR
ARROWHEAD PHARMACEUTICALS IN
-22.3%
12.6% of portfolio
KYMR
KYMERA THERAPEUTICS INC
-24.5%
6.8% of portfolio
RGNX
REGENXBIO INC
-21.7%
3.5% of portfolio
BCYC
BICYCLE THERAPEUTICS PLC
-22.6%
2.6% of portfolio

Sector Breakdown

Other66.5%
Healthcare33.5%

๐Ÿšช Exited Positionssold since Q4 2024

SLN
SILENCE THERAPEUTICS PLC
SOLD
$2.5M
โ€”
SUTRO BIOPHARMA INC
SOLD
$916

Changes from Q4 2024

NEW1 new position
โ†‘4 increased
โ†“7 decreased

Historical Filings

Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023