5AM Venture Management, LLC
•CIK: 1799883•Filing: Q4 2025
**5AM Venture Management, LLC** is a venture-focused fund managing $318M across 21 positions. The portfolio exhibits significant concentration in key technology and growth names, with top holdings including TRDA at $41.7M and CAMP at $36.0M. Further substantial allocations are directed toward TYRA ($27.1M), VRDN ($22.9M), and BLK ($22.1M). This structure indicates a conviction-driven, high-conviction approach within the venture landscape.
Total AUM
$318.1M
QoQ Performance
+16.5%
Positions
21
Top 10 Concentration
73.5%
Latest Filing
Q4 2025
Top Holdings Allocation
TRDA
CAMP
TYRA
VRDN
PHAR
ERAS
EYPT
MPLT
TRDA13.1%
CAMP11.3%
TYRA8.5%
VRDN7.2%
PHARVARIS7.0%
ERAS6.3%
EYPT6.0%
MPLT5.2%
📈 Biggest Buys
📉 Biggest Sells
Sector Breakdown
Other100.0%
🚪 Exited Positionssold since Q3 2025
Changes from Q3 2025
NEW1 new position
↑6 increased
↓2 decreased
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023