Data as of Q4 2025 (Dec 31, 2025)

Pivotal bioVenture Partners Investment Advisor LLC

โ€ขCIK: 1844645โ€ขFiling: Q4 2025

**Pivotal bioVenture Partners Investment Advisor LLC** manages $259M across a concentrated portfolio of 12 positions, signaling a focused approach within the biotechnology sector. The fund exhibits significant conviction in its top holdings, with PCVX representing the largest allocation at $63.3M. Further substantial exposure is evident in STT-PG ($45.7M) and ARQT ($39.7M), underpinning a deep-value or growth thesis across key drug discovery areas. This concentrated structure suggests active, high-conviction capital deployment within specialized life science opportunities.

Total AUM
$258.7M
QoQ Performance
+49.5%
Positions
12
Top 10 Concentration
99.2%
Latest Filing
Q4 2025

Top Holdings Allocation

PCVX
OCUL
ARQT
EVMN
ZBIO
TRVI
IMNM
PCVX24.5%
OCULIS17.7%
ARQT15.3%
EVMN12.8%
ZBIO8.3%
TRVI6.1%
IMNM6.1%
MPLT4.2%

๐Ÿ“ˆ Biggest Buys

EVMN
EVOMMUNE INC
NEW
12.8% of portfolio
MPLT
MAPLIGHT THERAPEUTICS INC
NEW
4.2% of portfolio
IMNM
IMMUNOME INC
+45.8%
6.1% of portfolio

๐Ÿ“‰ Biggest Sells

ARQT
ARCUTIS BIOTHERAPEUTICS INC
-35.6%
15.3% of portfolio
ZBIO
ZENAS BIOPHARMA INC
-24.0%
8.3% of portfolio
โ€”
OCULIS HOLDING AG
-0.5%
17.7% of portfolio

Sector Breakdown

Other100.0%

Changes from Q3 2025

NEW2 new positions
โ†‘1 increased
โ†“3 decreased

Historical Filings

Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023