SPHERA FUNDS MANAGEMENT LTD.
•CIK: 1496201•Filing: Q4 2025
SPHERA FUNDS MANAGEMENT LTD. oversees $509M in assets, with a concentrated portfolio of 98 positions. The fund's top holdings include TEVA, comprising 6.9% of the portfolio at $35.1M, and BIIB, representing 3.3% at $16.7M. Notable allocations also include MLYS, SNDX, and ASBA, totaling $48M, or 9.4% of the portfolio. The fund's largest sector exposure is to pharmaceuticals, with AZN, BKFDF, COGT, PRAX, and SNY collectively accounting for $64.1M, or 12.6% of assets under management.
Total AUM
$478.5M
+ $30.7M in options
QoQ Performance
+15.2%
Positions
93
+ 4 options
Top 10 Concentration
32.1%
Latest Filing
Q4 2025
Top Holdings Allocation
TEVA
TEVA6.9%
BIIB3.3%
MLYS3.2%
SNDX3.1%
NVMI3.1%
TSEM2.8%
COGT2.6%
AZN2.4%
📈 Biggest Buys
📉 Biggest Sells
Sector Breakdown
Other92.0%
Healthcare6.6%
Technology1.4%
🚪 Exited Positionssold since Q3 2025
+26 more exited positions
Changes from Q3 2025
NEW24 new positions
↑32 increased
↓27 decreased
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023