RA CAPITAL MANAGEMENT, L.P.
•CIK: 1346824•Filing: Q4 2025
RA Capital Management, L.P., led by renowned investor Raoul de Vitry d'Avaucourt, is known for its concentrated, high-conviction bets, currently holding 71 positions with a focus on biotech and healthcare. The fund has recently made notable moves by adding BCRX, PRAX, and OLMA, while exiting ETNBGBP and SRRK, and significantly increasing stakes in JBIO and DSGN, reflecting its aggressive growth strategy.
Total AUM
$9.8B
QoQ Performance
+20.3%
Positions
71
Top 10 Concentration
65.6%
Latest Filing
Q4 2025
Top Holdings Allocation
ASND
CDTX
RYTM
RNAGBP
PCVX
ASND22.5%
CDTX7.6%
RYTM7.3%
RNAGBP6.4%
PCVX5.1%
SION4.2%
NAMS3.4%
TYRA3.3%
📈 Biggest Buys
📉 Biggest Sells
Sector Breakdown
Other100.0%
🚪 Exited Positionssold since Q3 2025
—
METSERA INC
SOLD
$35.4M
+13 more exited positions
Changes from Q3 2025
NEW22 new positions
↑13 increased
↓8 decreased
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023