ARCH Venture Management, LLC
•CIK: 1274403•Filing: Q4 2025
ARCH Venture Management, LLC manages $652M across a concentrated portfolio of 9 positions. The fund maintains significant exposure to MAZE at $170.7M, followed by BEAM ($125.9M) and RAPP ($113.1M). These top three holdings represent over 60% of the reported assets under management. The structure indicates a deep-value, high-conviction approach targeting specific growth vectors.
Total AUM
$651.7M
QoQ Performance
+32.4%
Positions
9
Top 10 Concentration
100.0%
Latest Filing
Q4 2025
Top Holdings Allocation
MAZE
BEAM
RAPP
LYEL
VIR
ERAS
MAZE26.2%
BEAM19.3%
RAPP17.4%
LYEL13.0%
VIR12.0%
ERAS6.3%
GOSS3.8%
TXG1.8%
📈 Biggest Buys
TXG
10X GENOMICS INC.
NEW
1.8% of portfolio
📉 Biggest Sells
No reductions this quarter
Sector Breakdown
Other100.0%
🚪 Exited Positionssold since Q3 2025
—
CERO THERAPEUTICS HOLDINGS INC.
SOLD
$114.0K
Changes from Q3 2025
NEW1 new position
Historical Filings
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023